3GQQ, 3RBQ, 4GOJ, 4GOK909422248ENSG00000109103ENSMUSG00000002058Q13432Q9Z2R6NM_005148NM_054035NM_001330166NM_011676NM_001313985NM_001313986NM_001313987NM_001313988NP_001317095NP_005139NP_473376NP_001300914NP_001300915NP_001300916NP_001300917NP_035806Uncoordinated-119 (Unc-119) is a protein identified in a varieties of species including, C. elegans, humans, mice, zebrafish, rabbits, pig, calf, monkey, and protozoa.

[10] This pocket can bind to lauroyl (C12) and myristoyl (C14) acyltransferase side chains, functioning as a transporter or lipid-binding chaperone.

[11][12] The UNC-119 protein plays key roles in the movement and feeding in the C. elegans, because it is essential in the development and function of their nervous system.

When the organism possesses a mutated UNC-119, they have been shown to experience uncoordinated movement, a defect causing weak egg laying, and the inability to form dauer larvae.

It has been localized to the photo-receptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle.