Beta-sandwich

Beta-sandwich or β-sandwich domains consisting of 80 to 350 amino acids occur commonly in proteins.

[1] The number of strands found in such domains may differ from one protein to another.

β-sandwich domains are subdivided in a variety of different folds.

The L-type lectin domain is a variation of the jelly roll fold.

The C2 domain in its typical version (PKC-C2) is a β-sandwich composed of 8 beta-strands (β-strands).

Illustration of the β-sandwich from Tenascin C (PDB entry: 1TEN ​).