Beta-sandwich or β-sandwich domains consisting of 80 to 350 amino acids occur commonly in proteins.
[1] The number of strands found in such domains may differ from one protein to another.
β-sandwich domains are subdivided in a variety of different folds.
The L-type lectin domain is a variation of the jelly roll fold.
The C2 domain in its typical version (PKC-C2) is a β-sandwich composed of 8 beta-strands (β-strands).