Protochirotherium, also known as Protocheirotherium (‘first hand-beast’), is a Late Permian?-Early Triassic ichnotaxon (trace fossil) consisting of five-fingered (pentadactyl) footprints and whole tracks, discovered in Germany and later Morocco, Poland and possibly also Italy.

[5] Protochirotherium-like prints have also been documented from the Late Permian of Italy, possibly representing the oldest known fossils of mesaxonic archosauromorphs.

[2] Protochirotherium is the earliest known chirotheriid ichnotaxon, similar to later forms such as Chirotherium, Isochirotherium, and Brachychirotherium.

The shape of the large pes (foot) and smaller manus (hand) are typical among chirotheres, with a plantigrade posture and five clawed toes.

In the pes, the base of digit V has the form of a massive, rounded pad, which is more strongly expanded than in other chirotheres.