Protopanaxatriol (PPT) is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides.

[1] It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng).

In rats, the oral bioavailbility is about 3.7% and the half-life is 0.80 hours (when given as a PPD-PPT mixture).

PPT is unstable in acid, showing 40% degradation after 4 hours at 37°C both in pH 1.2 buffer solution and rat stomach contents.

[2] It is extensively metabolized in mice.