Psychotria carthagenensis, also known as amyruca, is a South American rainforest understory shrub from the coffee family, Rubiaceae.

[3] A study in 1972 based in gas chromatography–mass spectrometry method determined the presence of the alkaloids N,N-Dimethyltryptamine (DMT), N-monomethyltryptamine (MMT) and 2-methyl-1,2,3,4-Tetrahydro-β-carboline (MTHC) in the leaves.

[4] In a study in 1994 on ethanol extracts of the leaves showed negative results for the presence of alkaloids.

[6] Psychotria carthagenensis has been hybridised with the closely related P. viridis, by Australian nurseryman and scientist Darren Williams.

The cultivar Nexus was created in 2008, sold by the nursery Herbalistics, resulting in a plant with greater cold tolerance, increased growth rate.