[3] With a length of 13.9 km (8.6 mi), this highway extends from Mosquito to Puerto Diablo, passing through Isabel II (downtown Vieques).

The PR-200 East extends from the urban area to the municipal landfill in the Santa María sector, and the PR-200 West extends from Isabel II towards the southwest by the urban area, where Calle Carlos Le Brum is assigned to its intersection with Calle Muñoz Rivera.

Then it changes its name to Calle San Francisco to the south until the PR-997 junction, where it runs west through Florida, passing the PR-201 intersection (km 2.5) and reaching the Martineau sector, following to the Gringo Beach.

From this point it continues west, arrives at the Antonio Rivera Rodríguez Airport in Mosquito, passes PR-995 junction (km 6.6) until it reaches the old estrada of the military reservation (second gate) assigned to the municipality.

38 was the highway that led from Llave to Puerto Diablo through Mosquito, Florida and Isabel II,[7] while Road No.