[3] PR‑6 begins at a three-way junction with PR‑2 on the southern edge of the Villa España neighborhood, a gated and planned community in central Juan Sánchez.

(PR‑2 heads east toward the municipality of Guaynabo and west thorough the northern part of Bayamón.)

Shortly thereafter, the route turns north-northeast and reaches its northern terminus at a trumpet interchange with PR‑5 (Expreso Río Hondo [Río Hondo Expressway]).

(PR‑5 heads northeast toward San Juan and Carolina and southwest through Bayamón toward Aguas Buenas.

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