[5] This highway consists of two lanes in all of the entire length, one per direction, due to its rural characteristics.

It is also part of the Ruta Panorámica,[6] offering scenic views of southern Puerto Rico and the Cordillera Central.

[7] Near this highway, the Battle of Asomante took place, where Spanish and American troops met forces as part of the Spanish–American War of 1898.

[8] The following barrios are located along Puerto Rico Highway 723: Prior to its numerical designation, PR-723 was only known as Carretera de Pulguillas.

[12] The current numerical designation corresponds to the 1953 Puerto Rico highway renumbering, a process implemented by the Puerto Rico Department of Transportation and Public Works (Spanish: Departamento de Transportación y Obras Públicas) that increased the insular highway network to connect existing routes with different locations around Puerto Rico.