As with Puyo Puyo Tetris, the international release features English characters voices, allowing the player to change between the original Japanese and the English localized voices; the game interface is also available in French, German, Italian, Spanish, Traditional Chinese, Simplified Chinese and Korean.

As per its Japanese title, this game is aimed at eSports and thus focuses on competitive multiplayer, lacking the single player campaign mode prominently featured in most other Puyo Puyo games.

These characters include fan-favorites from the original Compile game series such as Arle Nadja and Dark Prince, as well as newer characters such as Ally, who debuted in the Japan-only Nintendo 3DS game Puyo Puyo Chronicle, even a handful of characters from Puyopuyo!!

The 2.02 update, released in August 2020, added two hidden characters, Rafisol and Paprisu, each of whom can be selected by inputting a specific button combination while selecting character.

Quest, as well as a selection of backgrounds and borders, all of which seem to be carried over from Puyopuyo!!