Pykestone Hill is a hill in the Manor Hills range, part of the Southern Uplands of Scotland.

The highest of a small group of hills near the village of Drumelzier, they are themselves a western portion of the Manor Hills.

[4] The summit is characterised by a series of sharp, protruding stones, from which the hill likely derives its name.

[5] It is often climbed from Drumelzier itself or Stanhope farm to the west, but ascents from the Manor Valley to the east are also possible.