Originally located in a Costa Mesa, California building adjacent to Emulex, it competed against its parent company in the market for Fibre Channel controllers for storage area networks.

[4] In May 2000, QLogic acquired Fibre Channel switch maker Ancor Communications for about $1.7 billion in stock.

[8] After attempting to use PathScale for cluster computing over InfiniBand, the compiler business was sold to SiCortex in August 2006.

[11] Simon Biddiscombe became chief executive in November 2010, until resigning in May 2013 after two years of falling revenue.

[13] QLogic announced it was being acquired by Cavium in June 2016, for about $1 billion over its balance sheet cash.

In 2014, QLogic signed a broad technology alliance agreement with Brocade Communications Systems and acquired its fibre channel and converged network adapter business.