[1][4] Ahmad was born in 1938 in the house of Muhammad Abdul Rab at Ziarat Kaka Sahib, Nowshera District, Khyber-Pakhtunkhwa, Pakistan.

[citation needed] His association with the Islamic Movement started in his school days when he first joined Islami Jamiat-e-Talaba, Pakistan.

After the resignation of Maulana Naeem Siddiqui, he was promoted to the office of Secretary General, Jamaat-e-Islami Pakistan in 1978.

In 2008, Syed Munawwar Hasan was elected to head Jamaat-e-Islami, when Qazi Hussain Ahmad chose not to run for the office.

[2] Qazi Hussain Ahmad traveled abroad widely to represent the Jamaat at the international forums, lead goodwill missions, and in a personal capacity to mediate in issues concerning Muslims, such as the Iran–Iraq War and the Persian Gulf War, the Balkan (Bosnia) crisis and the post-Soviet power struggle in Afghanistan.

Qazi Hussain resigned from the senate on 27 September and announced to start a long march against the Benazir's government.

[8] Qazi Hussain Ahmad died of a heart attack late in the evening on Saturday, 5 January 2013, at a son's house in Islamabad.