[2] She was possibly married to You Qiu (尤求), an artist influenced by her father and generally believed to be his son-in-law,[3] although this has been questioned by some scholars.

[2] She was also commissioned to create illustrations for Wang Chong's calligraphy of the narrative poem Nymph of the Luo River.

[3] Qiu Zhu's most famous subject is Guanyin, the bodhisattva of compassion especially appealing to women,[2] and her paintings of the goddess have been described as "mysteriously transcendent".

They are in gold ink on black paper, and were inspired by an album of woodblock prints by Ding Yunpeng (1547–1628) that had been based on a hand scroll by Li Gonglin.

[7] Her acclaimed painting, White Robed Guanyin, is in the collection of the National Palace Museum in Taipei.