[1] Quaid e Azam Medical College was founded on 2 December 1971 when its foundation stone was laid by the then Governor of Punjab, Lt Gen Attique-ur-Rehman (retd).

The founding Principal was Prof Dr Nawab Muhammad Khan.

Designed by Abdur Rahman Hye, it was the first endogenously designed Medical Campus by a Pakistani Architect and has the characteristics typical in A. R. Hye's style of architecture.

The design of the building incorporates natural climate control features, such as cross-ventilation, strategic placement of windows, and overhangs and courtyards to create shade.

This provides a natural protection against the hot and dry climate of Bahawalpur.