Quantitative computed tomography

Quantitative computed tomography (QCT) is a medical technique that measures bone mineral density (BMD) using a standard X-ray computed tomography (CT) scanner with a calibration standard to convert Hounsfield units (HU) of the CT image to bone mineral density values.

Douglas Boyd, PhD and Harry Genant, MD used a CT head scanner to do some of the seminal work on QCT.

Today, modern 3D QCT uses the ability of CT scanners to rapidly acquire multiple slices to construct three-dimensional images of the human body.

Using other non-IV contrast abdominal or pelvic scans such as a Virtual Colonography studies, the QCT exam can be performed without requiring any further image acquisition or consequent radiation dose to the patient.

Using pre-existing images, including CT colonography exams,[14] QCT allows for bone density screening without submitting the patient to any additional radiation exposure.

In medicine, peripheral quantitative computed tomography, commonly abbreviated pQCT, is a type of quantitative computed tomography (QCT), used for making measurements of the bone mineral density (BMD) in a peripheral part of the body, such as the forearms or legs as opposed to QCT that measures bone mineral density at the hip and spine.

High-resolution peripheral quantitative computed tomography (HR-pQCT) is better than DXA at detecting bone microarchitecture, modeling whole-bone geometry using 3-dimensional information from scans.

Image of cortical and trabecular bone of the spine by Quantitative computed tomography. Only the central trabecular portion is measured
Image of 3D volumetric QCT scan
Image of proximal femur bone projection