Queen Anne Creek is a tributary of Mill Creek, part of the Delaware River drainage basin in Bucks County, Pennsylvania.

Rising just north of Fallsington, it meets with its confluence with Mill Creek in Bristol Township.

[1] The watershed of Queen Anne Creek is 6.64 square miles (17.2 km2).

is 1184538,[2] U.S. Department of the Interior Geological Survey I.D.

[3] Rising in Falls Township just north of Fallsington at an elevation of 120 feet (37 m), Queen Anne Creek flows generally southwestward passing through Caroline Lake, then through Queen Anne Park, and Middletown Township Park to its confluence at Mill Creek's 5 River Mile at an elevation of 39 feet (12 m), resulting in an average slope of 18 feet per mile (3.4 m/km).