U.S. Route 59 passes through Queen City, leading north 22 miles (35 km) to Texarkana and south into Atlanta.

[4] As of the 2020 United States census, there were 1,397 people, 594 households, and 389 families residing in the city.

As of the census of 2000, there were 1,613 people, 660 households, and 440 families residing in the city.

30.0% of all households were made up of individuals, and 14.5% had someone living alone who was 65 years of age or older.

The majority of Cass County, including Queen City ISD, is in the service area of Texarkana College.