Quinic acid

This substance was isolated for the first time in 1790 by German pharmacist Friedrich Christian Hofmann in Leer from Cinchona.

[4] Its transformation into hippuric acid by animal metabolism was studied by German chemist Eduard Lautemann in 1863.

This four-carbon substrate is condensed with phosphoenol pyruvate to give the seven-carbon 3-deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) by the action of a synthase.

Two subsequent steps involving dehydroquinic acid synthase and a dehydrogenase afford the compound.

This acid is a versatile chiral starting material for the synthesis of pharmaceuticals.

Quinic acid
Quinic acid
Quinic acid
Quinic acid
NFPA 704 four-colored diamond Health 0: Exposure under fire conditions would offer no hazard beyond that of ordinary combustible material. E.g. sodium chloride Flammability 0: Will not burn. E.g. water Instability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogen Special hazards (white): no code
Shikimic acid , biosynthetic precursor to aromatic amino acids, is a close relative of quinic acid.