Quinoline alkaloids

Some quinoline alkaloids show antiseptic, convulsive or antineoplastic effects.

Alkaloids with a quinoline partial structure are widespread and are usually further subdivided according to their occurrence and biogenetic origin.

The quinoline alkaloids are mainly found in plants, as in Rutaceae and Rubiaceae, but also in microorganisms and animals.

Quinoline is furthermore comprised as a partial structure in the redox factor PQQ (pyrroloquinoline quinone) and in quinoenzymes.

The second precursor molecule is either a hemiterpene or a monoterpene (e.g. secologanine in cinchona alkaloids).