Quinto Romano (Milanese: Quint) is a district (quartiere) of Milan, Italy, part of the Zone 7 administrative division of the city.

Before being annexed to Milan, it was an autonomous comune (until 1869) and a frazione of Trenno (from 1869 to 1923).

Quinto Romano was a rural district until the 1960s; the land was then partitioned into 8-9 cascine (farms).

In the following decades, as most of the Milanese rural outskirts, Quinto experienced a quick urbanization process as a consequence of the economic boom of northern Italy and immigration from the south, which caused a quick expansion of Milan and other industrial cities.

As is the case with other outskirts that have experienced this rapid development in those decades, Quinto gained the reputation of a socially and economically degraded district.