[2] From the southern end, the road begins at a junction on the N1 at Tokor in the Ketu South Municipal District of the Volta Region.

It continues via Kpoglu close to the international border with Togo, leaving the district.

The R10 then traverses the Akatsi North District, passing through Ave-Xevi, Ave-Afiadenyingba and Ave-Dakpa, the capital.

The R10 then heads west, away from the border ending at Ho where it meets the Ho-Adidome Road, which is a section of the R28 from Fume to Sogakope.

[2] Local citizens had in the past expressed displeasure at the level of maintenance of the Ho-Denu road and other projects.