The R369 is a Regional Route in South Africa that connects the R357 near Prieska with Colesberg via Hopetown.

It then continues east for about 90 kilometres to meet the N12 at a staggered intersection in Hopetown.

It continues south-east, following the Orange River, to the town of Orania, before again intersecting with the R387, this time at its eastern terminus.

While co-signed with the R48, it bypasses Vanderkloof to the west and passes through Petrusville.

Leaving the R48 south of Petrusvile, the route heads south-south-east to end near Colesberg at an interchange with the N1, the R717 and the R58.