The R50 is a provincial route in South Africa that connects Pretoria with Standerton via Delmas and Leandra.

It begins as Delmas Road and heads south-east, passing through Erasmuskloof and meeting the M10 metropolitan route (Solomon Mahlangu Drive) before passing in-between Wingate Park and Elardus Park and becoming the eastern border of the Rietvlei Nature Reserve.

[2]: 29  They are cosigned as one road up to the four-way junction of Bapsfontein, where they meet the northern terminus of the R51 route from Daveyton/Springs.

[5][6] The R50 runs another 30 km to the town of Delmas, crossing the border between Gauteng and Mpumalanga.

[2]: 21  The R50 journeys another 80 km south-east, intersecting with the R547 road near Brendan Village (staggered junction; cosigned for a few kilometres), to the town of Standerton.