The R559 is a Regional Route in Gauteng, South Africa that connects Protea Glen with Carletonville via Randfontein.

[1] The R559 begins at a junction with the R558 road in Protea Glen, Soweto, just north of the R558's intersection with the N12.

It goes north-west for 17 kilometres to reach a junction with the R28 road in the southern suburbs of Randfontein.

[1] From Randfontein, it turns to the south-west and goes for 22 kilometres, through Hillside, to reach a junction with Station Street.

It becomes Station Street westwards and goes for 17 kilometres to enter the towns of Oberholzer and Carletonville.