592419418ENSG00000113319ENSMUSG00000021708O14827P70392NM_006909NM_009027NP_008840NP_033053Ras-specific guanine nucleotide-releasing factor 2 is a protein that in humans is encoded by the RASGRF2 gene.

[5] RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state.

Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.

[supplied by OMIM][5] Variations in this gene has been shown to be linked to the propensity to binge drink by teenagers.

This article on a gene on human chromosome 5 is a stub.