1LDJ, 1LDK, 1U6G, 2HYE, 2LGV, 3DPL, 3DQV, 3RTR, 4F52, 4P5O9978100043674ENSG00000100387n/aP62877n/aNM_014248XM_006525232XM_006536722XM_006537452NP_055063n/aRING-box protein 1 is a protein that in humans is encoded by the RBX1 gene.

[4][5] This gene encodes an evolutionarily conserved protein that interacts with cullins.

The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization.

It also may be involved in the regulation of protein turn-over.

[6] RBX1 has been shown to interact with: