[citation needed] However, several recent studies suggest that the activity of p70S6K plays a more positive role in the increase of autophagy.

Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines.

mTOR can be activated via an AND-gate-like mechanism at the lysosome, integrating signals about growth factors and bioavailability of important molecules.

Inhibition of the S6K1 protein, or a lack of it, slows the production of adipose (fat) cells by disrupting and retarding the initial "commitment stage" of their formation.

[11] Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines.