RU-24,969 is a serotonergic drug used in scientific research.

[1][2] It also has affinity for the serotonin 5-HT5A, 5-HT5B, and 5-HT7 receptors.

[3] The drug produces MDMA-like locomotor hyperactivity in animals and this is thought to be mediated by activation of both serotonin 5-HT1A and 5-HT1B receptors.

[4][1][5][6][7] As with other serotonin 5-HT1B receptor agonists such as CP-94,253, RU-24,969 has also been found to increase the reinforcing properties of cocaine in animals, suggesting a role for serotonin 5-HT1B receptors in cocaine addiction as well.

[9] This drug article relating to the nervous system is a stub.