She joined the Fareynikte Partizaner Organizatsye, formed that same year by poet Abba Kovner.
Margolis wrote"Everyone was anxious to fight... Our mission was to acquire weapons, complete militarily preparations, all with the aim of provoking an uprising in the ghetto.
They contracted typhus but lived to continue their work with the resistance movement, joining a new unit and blowing up German infrastructure.
[4][9] Margolis found and published the long-lost diary of Kazimierz Sakowicz, a Polish Christian journalist who witnessed the Ponary massacre outside Vilnius, where tens of thousands of Jews were murdered.
[6] Beginning in 2008, the Lithuanian prosecutor general wanted to question Margolis as part of the investigation of the Koniuchy massacre when Soviet and Jewish partisans killed at least 38 civilians.