She is a Professor in the Departments of Psychiatry, and Pharmacology and Toxicology at the University of Toronto and a Canada Research Chair in Pharmacogenomics.
[3] Following her fellowship, Tyndale joined the Centre for Addiction and Mental Health (CAMH) and accepted a faculty position at U of T in their Departments of Psychiatry, and Pharmacology and Toxicology in 1996.
[5] This revelation showed that people who metabolize the drug slowly are less likely to become smokers, because the negative effects of nicotine last longer for them.
[7] Throughout her tenure at the institution, Tyndale continued her research into tobacco and conducted the study to demonstrate the direct effect of nicotine on drug metabolism in the central nervous system.
[8] She also co-led a randomized clinical trial to determine how long nicotine stays in the body between cigarettes and after users stop smoking.