The Radio Regulations of the International Telecommunication Union (ITU) define interference as being detrimental to radio astronomy if it increases measurement uncertainty by 10%.
In particular, the applicable regulation is known as ITU-R Recommendation RA.769, "Protection criteria used for radio astronomical measurements".
[1] Quiet zones are located in areas that are sparsely populated, and may be enforced based on government legislation.
[3] Formal radio quiet zones exist around many observatories,[4] including the Murchison Radio-astronomy Observatory in Australia,[1] the National Radio Astronomy Observatory and the Sugar Grove Station in West Virginia, United States (the United States National Radio Quiet Zone),[2] the Itapetinga Radio Observatory in Brazil,[5] and MeerKAT in South Africa as examples.
The ITU has recommended designating two locations in outer space as radio quiet zones: the shielded zone on the Moon's far side, and the Sun-Earth Lagrangian point L2.