Marie Curie and André-Louis Debierne used it in their original separation of radium from barium.
Its color gradually changes to yellow with aging, whereas contamination by barium may impart a rose tint.
[8][9] Radium-223 dichloride (USP, radium chloride Ra 223), tradename Xofigo (formerly Alpharadin), is an alpha-emitting radiopharmaceutical.
Bayer received FDA approval for this drug to treat prostate cancer osteoblastic bone metastases in May 2013.
[citation needed] One dose (50 kBq/kg) in an adult is about 60 nanograms; this amount is 1/1000 the weight of an eyelash (75 micrograms).