He was a member of the Lithuanian Council of Lords and one of the most influential people in the Grand Duchy of Lithuania during his lifetime.

[1] Radvila Astikas was Voivode of Trakai (1466–77) and Castellan of Vilnius (1475–77), as well as Grand Marshal of Lithuania (1433–34, 1463–74).

[3] There were rumors that in 1440 Astikas was considered as a candidate to the Grand Duke's throne instead of Casimir Jagiellon, but they should be taken with a grain of salt.

His most important patrimonial possession was Musninkai where he funded a Catholic church.

[1][9] Astikas and his wife Eudoxia were the great-great-great grandparents of Elizabeth Báthory.