In the mid-1950s, the University of Western Australia launched an appeal for funds to create a medical school, and the Raines were approached directly for a contribution.
[1] In September 1956 Joe suffered a severe stroke caused by arteriosclerosis, resulting in paralysis.
[1] Mary inherited Joe's estate, worth £153,906, and donated it to the University of WA[b] to establish the Arnold Yeldham and Mary Raine Medical Research Foundation, with the money to be invested and initially used for research into arteriosclerosis.
[1][3] In 1957 Raine made a new will, leaving small amounts to some friends and family – she had no children of her own – with the bulk of her estate to go the University, for the purposes of finding a cure for the illness that killed Joe.
[1] The foundation financially supports the Western Australian Pregnancy Cohort (Raine) Study, one of the largest cohorts of pregnancy, childhood, adolescence and early adulthood to be carried out anywhere in the world.