In 2019, he appeared in another Alt Balaji web series Coldd Lassi Aur Chicken Masala opposite Divyanka Tripathi.

[15] He started working with a Delhi based production house and also modelled for brands like LML, Green Label Whiskey, Videocon and many more.

[19] He portrayed the character of Sujal Garewal who is 6 feet tall, dark handsome and rich, a Mills & Boonish hero and a scorned lover.

[21] In 2005, he was seen as the RAW Field Officer Varun Awasthi in Ketan Mehta's action television series, Time Bomb 9/11.

[26] Film critic Taran Adarsh from Bollywood Hungama reviewed "Rajeev Khandelwal is remarkable in the title role.

The film would've fallen flat had it been entrusted to an inferior actor, but Rajeev lends the right shades and emerges triumphant.

[27]CNN-IBN's Rajeev Masand added, "Uninhibited, spontaneous and blessed with unmistakable presence, Khandelwal holds the screen like a seasoned artist.

[30] He played the role of Inspector Arvind Mathur, who is assigned by the Police Commissioner to solve a case unofficially, as he is on suspension after throwing a corporator from the first floor of his own house for allegedly beating up a woman.

He played the role of DJ, Raunak [Rajeev Khandelwal], who gets addicted to drugs and alcohol and loses his hearing ability.

[32] Subhash K. Jha of NDTV reviewed "his performance is so accomplished that he proves, not for the first time, that he's among the most engaging actors today.

"[33] Taran Adarsh added "Playing an emotionally unstable character is always taxing and an edgy journey for any actor, but Rajeev emerges triumphant with a bravura performance.

[40] Zee News reviewed his performance as "In this film, Rajeev has proven, yet again, the limit to which his acting skills reach, which – no doubts about that – is the sky.

[47] Khandelwal next acted in the adventure film, Peter Gaya Kaam Se alongside Lekha Washington and Prashant Narayanan.

"[51] Faheem Ruhani of India Today reviewed:"After watching this film you miss the Rajeev Khandelwal who debuted in the brilliantly made Aamir (2008).

[53] In 2015, Khandelwal appeared in the Indo-Australian film Salt Bridge where he played the role of Basant, an Indian migrant who arrives in Australia and meets an Australian woman.

[56] He played the role of Kabir Sharma, the Editor-in-Chief of KKN with a horrid past who falls passionately for a junior reporter, Ananya Kashyap.

[63][64] In 2016, Khandelwal hosted a documentary film, The Legend Of Jaggannath, which takes a behind-the-scenes look at the Indian religious festival of Rath Yatra.

[66] (Aamna Shariff) (Shiv Panditt, Kalki Koechlin, Gulshan Devaiah, Kirti Kulhari, Neil Bhoopalam)