The Rand McNally Building was an early skyscraper at 160–174 Adams Street in Chicago, Illinois, built in 1889 and demolished in 1911.

Designed by Burnham and Root, it was the world's first all-steel framed skyscraper.

It was 45 m (148 ft) tall,[1] had 10 stories, 16 stores, and 300 offices, but the main tenant was Rand, McNally & Co., printers and publishers, with 900 employees.

The general offices of the Chicago, Milwaukee & St. Paul Railway were located here on the 2nd and 3rd floors,[2] as were the headquarters of the World's Columbian Exposition, on the 4th and 5th.

For many years, it housed the headquarters of the City National Bank & Trust Company.