A random positioning machine, or RPM, rotates biological samples along two independent axes to change their orientation in space in complex ways and so eliminate the effect of gravity.

One frame is positioned inside the other giving a very complex net change of orientation to a biological sample mounted in the middle.

The vector-averaging by Airbus' algorithm doesn't average out the vector to null but to a percentage representing simulated partial-gravity.

However, technological advances made it possible to simulate microgravity in Random Positioning machines, which find vast implications in modern research.

A secondary effect part of this is the shear forces created by the fluid dynamics of the cell culture medium.