All of the organization's published work has been released under Creative Commons non-commercial licenses, including those contributing to the Open COVID Pledge.

In March 2020, Preston Estep sent an email to several associates in an effort to determine whether any open-source vaccine projects were underway.

[citation needed] Several of RaDVaC's core members and numerous others have engaged in self-experimentation to assess both the safety and efficacy of the vaccine formulations.

[citation needed] In December 2021 ACX Grants announced that RaDVaC had been awarded US$100,000 "to make open-source modular affordable vaccines.

"[22] In May 2022 RaDVaC tweeted it had been awarded US$2.5 million from Balvi,[23] a moonshot anti-covid effort established by Vitalik Buterin.