Reef Karim is a television personality, international speaker, author, and osteopathic physician.

[2] He subsequently completed a joint internship in internal medicine/psychiatry/neurology, a residency in psychiatry, and a fellowship in addiction medicine, all at UCLA.

[12] He is a contributor for the Huffington Post, and his work has been profiled in Forbes and the Christian Science Monitor.

[13][14] As an actor, Karim played the lead in the Indie movie Flavors, with supporting roles in Lost Transmissions (2019) (with Simon Pegg), Laurel Canyon (2002) (with Christian Bale), Veep (2017) (with Julia Louis-Dreyfus), Lords of Dogtown (2005) (with Heath Ledger), Claire's Cambodia and appeared in The Breakup Girl(2015), Fit to Be Tied (2014), Posey (2012), Goodbye My Friend (2011), The Whisperers (2009), Night of Henna (2005), Russians in the City of Angels (2003), and Flavors (2004).

He has also hosted multiple television shows, including Outrageous Acts of Psych, Broken Minds and House of Clues.