Reese is a village in Tuscola and Saginaw counties in the U.S. state of Michigan.

According to the United States Census Bureau, the village has a total area of 1.35 square miles (3.50 km2), all land.

The Saginaw-Watrousville plank road was opened in 1871, which increased access to the community from Saginaw and the surrounding area.

In 1873, the Detroit and Bay City railroads were built and Hudson B. Blackman plotted a tract of land adjacent to the original community (near the current intersection of Saginaw and Meridian streets) and named it Reese, in honor of Alvin H. Reese the railroad superintendent.

They lived in tents in the dense forest of the area in what is now Camp Street.

In 1873, William's brother, Joseph, came to the area and opened a hotel near the corner of Reese and Saginaw roads.

He was the fourth family to move to the area, with the others being his brother, the Woodruffs, and the Rogerses.

In September 1872, Asenath M. Rogers, Roberts’ wife, surveyed and platted eleven acres and called it Gates.

Hudson B. Blackman then platted a tract of land adjoining Gates, and called it Reese, in honor of the railroad superintendent.

Thomas Haniford and Michael Doyle probably worked for that same railroad, and Eustius Gall, born in Switzerland, was an engineer.

With the railroad station at the east end of town being called Reese, the post office of Gates at the west end eventually merged, the entire village and surrounding area becoming known as Reese.

In 1877, Reese was described as the railroad and trading point for a large section of farming country.

In the early 1900s, the railroad also was used by local farmers to ship hogs and cattle to Detroit.

Reese Crossing was not an interlocking but it was protected by a target that was set by approaching train crews.

The target was set vertical for a Michigan Central movement on the Denmark Jct.

In 1988, Huron and Eastern Railway purchased the rail line which is still in operation today.

Reese area farmers are one of the Huron & Eastern Railway's major shippers.

The left side of the building was the original structure which was remodeled and increased in size in 1912.

That structure remained, with renovations and additions, until it was torn down in 1962. it was replaced by the present middle school building which was erected from 1957 to 1966.

Reese 44 members were the first teachers in Michigan fired for demanding a fair contract by striking.

Corn, soybeans, navy beans, and sugar beets are the major crops produced.