[2] Her mother named her after Regan MacNeil, the fictional character possessed by a demon in the horror film The Exorcist.

[2][3] She captained her high school soccer team at Iowa City West, where she scored 93 goals in four years.

[2] She initially committed to Vanderbilt, but after its head coach resigned, she switched to Northwestern over offers from Iowa, Nebraska, TCU, and Clemson.

[10][11] She then signed her first professional contract with Swedish club KIF Örebro DFF on April 8, 2022, for the rest of the year.

[12] She entered the usual starting lineup following the departure of Anna Sandberg to Häcken and was converted from an attacking midfielder to an offensive-minded left back.

[17][18] She made her NWSL debut on March 30, coming on for Bia Zaneratto late in a 4–2 win against Angel City FC.