[1][2] High Street was the home of the wealthiest townspeople in the 1580s, and the houses dating from the rebuilding form the finest examples of post-fire architecture in the town.
[3] The modern street still contains many other good examples of Elizabethan timber-framed buildings, all of which date from after the fire; these include the Queen's Aid House, number 46 and the grade-I-listed Crown Inn.
[4] The bend in the High Street which Regent House now occupies follows the outer wall of the Norman Nantwich Castle.
[5][7][8] The existing Regent and Warwick House is believed to have been built shortly after the 1583 fire,[4] which destroyed all the buildings on the west side of High Street, together with much of the town east of the River Weaver.
Sash windows were added, and the original triangular gables were replaced by a section with timber uprights which imitated the parapets of late Georgian townhouses.