Reggie Grimes II (born May 6, 2002) is an American college football defensive end for the Memphis Tigers.

Grimes grew up in Antioch, Tennessee and initially attended Mount Juliet High School.

[2] Grimes was rated a five-star recruit and committed to play college football at Oklahoma over offers from Alabama, Florida State, South Carolina, Tennessee and Vanderbilt.

[3][4] Grimes played in eight games during his freshman season at Oklahoma and made six tackles with one sack.

[5] He played in all 12 of the Sooners' games with five starts as a sophomore and finished the season with 18 tackles with two sacks and two forced fumbles.