The Basilica di Santa Maria Regina degli Apostoli alla Montagnola, entrusted to the care of the Society of St. Paul (Paolini), is located in Via Antonino Pio, in the Ostiense quarter of the city of Rome, Italy.

Built between 1945 and 1954, the church was designed by architect Leone Favini and is inspired by Roman Baroque architecture.

Santagata, depicting Marian images, among them a fresco showing the Virgin Mary seated among the Apostles as the Holy Spirit descends upon them.

The Cardinal priests who have been assigned to this title to date are: On October 26, 1976, the church was established as a parish church of the diocese of Rome by the decree Pastorali munere issued by the Cardinal Vicar, Ugo Poletti.

Despite the similar title, the church is unrelated to the Pontifical Athenaeum Regina Apostolorum, an educational institute in Rome directed by the Congregation of the Legionaries of Christ.