Algernon was the fourth of five sons born to the former Lady Rosa Nugent and Fulke Greville-Nugent, 1st Baron Greville.

His sister was Hon Mildred Charlotte Greville-Nugent, who married Alexis Huchet, Marquis de la Bedoyére.

[1] He held the Irish parliamentary seat of Longford, vacated by his father on his elevation to the peerage, from 31 December 1869, defeating John Martin.

He had to relinquish the seat in May 1870 due to Judge Fitzgerald overturning the election result on the grounds of voting irregularities.

[4] His illegitimate son, Reginald Charles Fulke Greville, born 19 August 1866, was better known after changing his surname to Maugham (following a close friendship with the writer W. Somerset Maugham's great-aunt Julia) as the author of numerous books about Africa, and his most well-known work, Jersey under the Jack Boot.