The Reina Nacional de Belleza Miss República Dominicana 2006 pageant was held on October 17, 2005.
The chosen winner represented the Dominican Republic at the Miss International 2006 pageant which was held in Tokyo.
The second runner up represented the country in Reina Nacional del Café.
The fourth runner up represented the country in Reina Mundial del Banano.
The fifth runner up represented the country in Miss Tourism Queen International 2006.