The municipality is bordered on the north by Caibarién, to the south by Camajuaní and Placetas, and to the east by Yaguajay (in Sancti Spíritus Province).

Remedios has 10 consejos populares which include: El Carmén, San Salvador, and Hermanos Herrada, in the city of Remedios and nearby settlements, and Heriberto Duquesne, Buena Vista, General Carrillo, Zulueta, Tahón-Francisco Pérez, Remate de Ariosa, and Circunscripciónes Directas (Chiquito Fabregat or San Agustín).

According to legend, Vasco, in order to avoid tax payments to the Crown, kept the village hidden from the knowledge of the King of Spain as long as he could.

Through his wife, the daughter of the Cacique of Sabaneque, Vasco received a huge land grant as a personal fief from Governor Diego Velázquez de Cuéllar, as stipulated by Spanish law.

The economic growth relied on agriculture and cattle raising, and this eventually became one of the major beef suppliers to Spain's Florida colonies.

), a major dispute arose among the settlers, led by Father Gonzalez de la Cruz, who claimed that satanic forces had taken hold of the place.

The Spanish Crown sent a Royal Decree dated 29 January 1684 transferring the settlement to another place in order to avoid the demons.

[5] The main attraction in the Plaza Isabel II is the Iglesia Mayor of San Juan Bautista, containing 13 decorated gold altars.

In a renovation that took place between 1944 and 1954, with donations by Cuban millionaire philanthropist Eutimio Falla Bonet, the real gold under coats of paint was re-discovered.

It is surrounded by colonial buildings, beautiful monuments, trees, palms and a gazebo, like many towns in Cuba that were designed according to a Spanish urban standard.

According to tradition, when the bells of the Iglesia Parroquial Mayor (Major Parochial Church) toll at 9 o'clock on the night of December 24, two neighborhoods make public their creativeness and efforts made during the entire year to participate in the competition.