Morally corrupt from his work, he does not weigh the consequences and decides to extract Ren's brain.
[1] Stimpy operates a drill intended for lobotomy, but uses it to open a heavily guarded jar where he acquires his hazardously sharp scalpel.
He successfully extracts Ren's brain and spinal column, with four nerves for navigation, making the experiment a triumph.
[1] Ren awakes, but does not realize his situation; he sees the time and gets to work, able to drive without problems.
Ren's body manages to broadcast the event on television, killing the entire population of the United States and the world (including Stimpy) from shock at the sight and destroying Earth ("Thus endeth the Republican Party as we know it!").
[2] Kricfalusi intended it to be the series' next cult classic, noting this when he reacted to the final product with no involvement from him in the home media release.
[4] The episode eventually aired during a Nickelodeon-"commissioned" fifth season, with Reccardi departing immediately after its production.