Seyssaud was born on 16 June 1867 in Marseille, but spent his childhood at his ancestral home of Pezet house (Villes-sur-Auzon).

[1] Noted for his powerful temperament and his bold, brightly coloured palette, Seyssaud together with Louis Valtat has been described as a precursor of Fauvism.

His marriage on 11 January 1899 to Louise Philibert gave him the opportunity to settle in Villes-sur-Auzon, where he chose Mont Ventoux and the gorges of the Nesque as his pictorial themes.

On 27 April 1901, François Thiébault-Sisson wrote in Le Temps about Seyssaud:We should give first place here to someone who is like no one else, who is part of no group and who owes nothing to anyone except himself.

[1] His features are preserved in the portrait painted by Pierre Ambrogiani [fr] and kept by the Musée municipal Paul Lafran in Saint-Chamas.