René Arredondo (born 15 June 1961) is a Mexican former WBC Jr. Welterweight champion.
He mainly fought in Mexico for first three years, then moved the main battlefield to the United States since 1983, and won the World Boxing Council (WBC) junior welterweight title by beating Lonnie Smith via the fifth round on a technical knockout (TKO) in 1986.
In his first defense, he again lost the title to Roger Mayweather via the sixth round on a TKO.
However, Arredondo continued to fight, capturing the North American Boxing Organization (NABO) light middleweight title against Jeff Leggett via a 10th-round TKO in Tijuana, Baja California in August 1995, Mexico.
He is currently working in Los Angeles at several boxing gyms, where he has a thriving personal training business.